Epithelial miR-141 regulates IL-13–induced airway mucus production

IL-13–induced goblet cell metaplasia contributes to airway remodeling and pathological mucus hypersecretion in asthma. miRNAs are potent modulators of cellular responses, but their role in mucus regulation is largely unexplored. We hypothesized that airway epithelial miRNAs play roles in IL-13–induc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Siddiqui, Sana, Johansson, Kristina, Joo, Alex, Bonser, Luke R., Koh, Kyung Duk, Le Tonqueze, Olivier, Bolourchi, Samaneh, Bautista, Rodriel A., Zlock, Lorna, Roth, Theodore L., Marson, Alexander, Bhakta, Nirav R., Ansel, K. Mark, Finkbeiner, Walter E., Erle, David J., Woodruff, Prescott G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2021
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021117/
https://ncbi.nlm.nih.gov/pubmed/33682796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139019
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