EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis

Glioblastoma (GBM) are aggressive brain tumors with limited treatment options. Cancer stem-like cells (CSLCs) contribute to GBM invasiveness, representing promising targets. BAL101553, a prodrug of BAL27862, is a novel small molecule tubulin-binding agent, promoting tumor cell death through spindle...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bergès, Raphaël, Tchoghandjian, Aurélie, Sergé, Arnauld, Honoré, Stéphane, Figarella-Branger, Dominique, Bachmann, Felix, Lane, Heidi A., Braguer, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055546/
https://ncbi.nlm.nih.gov/pubmed/32165998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27374
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados