Glycolipids Recognized by A2B5 Antibody Promote Proliferation, Migration, and Clonogenicity in Glioblastoma Cells

A2B5+ cells isolated from human glioblastomas exhibit cancer stem cell properties. The A2B5 epitope belongs to the sialoganglioside family and is synthetized by the ST8 alpha-N-acetyl-neuraminidase α-2,8-sialyltransferase 3 (ST8SIA3) enzyme. Glycolipids represent attractive targets for solid tumors;...

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Publicat a:Cancers (Basel)
Autors principals: Baeza-Kallee, Nathalie, Bergès, Raphaël, Soubéran, Aurélie, Colin, Carole, Denicolaï, Emilie, Appay, Romain, Tchoghandjian, Aurélie, Figarella-Branger, Dominique
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769647/
https://ncbi.nlm.nih.gov/pubmed/31466399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091267
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