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Proscillaridin A exerts anti-tumor effects through GSK3β activation and alteration of microtubule dynamics in glioblastoma

Glioblastoma (GBM) is characterized by highly aggressive growth and invasive behavior. Due to the highly lethal nature of GBM, new therapies are urgently needed and repositioning of existing drugs is a promising approach. We have previously shown the activity of Proscillaridin A (ProA), a cardiac gl...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Berges, Raphael, Denicolai, Emilie, Tchoghandjian, Aurélie, Baeza-Kallee, Nathalie, Honore, Stephane, Figarella-Branger, Dominique, Braguer, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155148/
https://ncbi.nlm.nih.gov/pubmed/30250248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1018-7
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