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Proscillaridin A exerts anti-tumor effects through GSK3β activation and alteration of microtubule dynamics in glioblastoma

Glioblastoma (GBM) is characterized by highly aggressive growth and invasive behavior. Due to the highly lethal nature of GBM, new therapies are urgently needed and repositioning of existing drugs is a promising approach. We have previously shown the activity of Proscillaridin A (ProA), a cardiac gl...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Berges, Raphael, Denicolai, Emilie, Tchoghandjian, Aurélie, Baeza-Kallee, Nathalie, Honore, Stephane, Figarella-Branger, Dominique, Braguer, Diane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155148/
https://ncbi.nlm.nih.gov/pubmed/30250248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1018-7
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