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Anti-Migratory Effect of Vinflunine in Endothelial and Glioblastoma Cells Is Associated with Changes in EB1 C-Terminal Detyrosinated/Tyrosinated Status

We previously showed that vinflunine, a microtubule-targeting drug of the Vinca-alkaloid family exerted its anti-angiogenic/anti-migratory activities through an increase in microtubule dynamics and an inhibition of microtubule targeting to adhesion sites. Such effect was associated with a reduction...

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Bibliografske podrobnosti
Main Authors: Rovini, Amandine, Gauthier, Géraldine, Bergès, Raphaël, Kruczynski, Anna, Braguer, Diane, Honoré, Stéphane
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672205/
https://ncbi.nlm.nih.gov/pubmed/23750272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065694
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