ROS-mediated EB1 phosphorylation through Akt/GSK3β pathway: implication in cancer cell response to microtubule-targeting agents

Microtubule-targeting agents (MTAs) are largely administered in adults and children cancers. Better deciphering their mechanism of action is of prime importance to develop more convenient therapy strategies. Here, we addressed the question of how reactive oxygen species (ROS) generation by mitochond...

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Main Authors: Grand, Marion Le, Rovini, Amandine, Bourgarel-Rey, Veronique, Honore, Stephane, Bastonero, Sonia, Braguer, Diane, Carre, Manon
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102819/
https://ncbi.nlm.nih.gov/pubmed/24930764
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