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ROS-mediated EB1 phosphorylation through Akt/GSK3β pathway: implication in cancer cell response to microtubule-targeting agents

Microtubule-targeting agents (MTAs) are largely administered in adults and children cancers. Better deciphering their mechanism of action is of prime importance to develop more convenient therapy strategies. Here, we addressed the question of how reactive oxygen species (ROS) generation by mitochond...

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Bibliografiske detaljer
Main Authors: Grand, Marion Le, Rovini, Amandine, Bourgarel-Rey, Veronique, Honore, Stephane, Bastonero, Sonia, Braguer, Diane, Carre, Manon
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102819/
https://ncbi.nlm.nih.gov/pubmed/24930764
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