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Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases
Acetylcholinesterase (AChE) is a pivotal enzyme in neurotransmission. Its inhibition leads to cholinergic crises and could ultimately result in death. A related enzyme butyrylcholinesterase (BChE) may act in the CNS as a co-regulator in terminating nerve impulses and is a natural plasma scavenger up...
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| 出版年: | Toxicol Lett |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053431/ https://ncbi.nlm.nih.gov/pubmed/31863869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2019.12.016 |
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