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The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine (m(3)A), which in Escherichia coli is removed by m(3)A-DNA glycosylase I (T...
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| Gepubliceerd in: | Front Microbiol |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7051996/ https://ncbi.nlm.nih.gov/pubmed/32158436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00263 |
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