लोड हो रहा है...
Structural basis for enzymatic excision of N(1)-methyladenine and N(3)-methylcytosine from DNA
N(1)-methyladenine (m(1)A) and N(3)-methylcytosine (m(3)C) are major toxic and mutagenic lesions induced by alkylation in single-stranded DNA. In bacteria and mammals, m(1)A and m(3)C were recently shown to be repaired by AlkB-mediated oxidative demethylation, a direct DNA damage reversal mechanism....
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852788/ https://ncbi.nlm.nih.gov/pubmed/17396151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601662 |
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