Structural basis for enzymatic excision of N(1)-methyladenine and N(3)-methylcytosine from DNA

N(1)-methyladenine (m(1)A) and N(3)-methylcytosine (m(3)C) are major toxic and mutagenic lesions induced by alkylation in single-stranded DNA. In bacteria and mammals, m(1)A and m(3)C were recently shown to be repaired by AlkB-mediated oxidative demethylation, a direct DNA damage reversal mechanism....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Leiros, Ingar, Nabong, Marivi P, Grøsvik, Kristin, Ringvoll, Jeanette, Haugland, Gyri T, Uldal, Lene, Reite, Karen, Olsbu, Inger K, Knævelsrud, Ingeborg, Moe, Elin, Andersen, Ole A, Birkeland, Nils-Kåre, Ruoff, Peter, Klungland, Arne, Bjelland, Svein
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852788/
https://ncbi.nlm.nih.gov/pubmed/17396151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601662
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados