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The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine (m(3)A), which in Escherichia coli is removed by m(3)A-DNA glycosylase I (T...
Kaydedildi:
| Yayımlandı: | Front Microbiol |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7051996/ https://ncbi.nlm.nih.gov/pubmed/32158436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00263 |
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