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Peripheral Opioid Receptor Antagonists for Opioid-Induced Constipation: A Primer on Pharmacokinetic Variabilities with a Focus on Drug Interactions

Opioid analgesics remain a treatment option for refractory acute and chronic pain, despite their potential risk for abuse and adverse events (AEs). Opioids are associated with several common AEs, but the most bothersome is opioid-induced constipation (OIC). OIC is often overlooked but has the potent...

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Detalhes bibliográficos
Publicado no:J Pain Res
Main Authors: Gudin, Jeffrey, Fudin, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049282/
https://ncbi.nlm.nih.gov/pubmed/32158255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S220859
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