Peripherally acting μ-opioid receptor antagonists as treatment options for constipation in noncancer pain patients on chronic opioid therapy

Opioid-induced constipation (OIC), a prevalent and distressing side effect of opioid therapy, does not reliably respond to treatment with conventional laxatives. OIC can be a treatment-limiting adverse event. Recent advances in medications with peripherally acting μ-opioid receptor antagonists, such...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Patient Prefer Adherence
Hauptverfasser: Pergolizzi, Joseph V, Raffa, Robert B, Pappagallo, Marco, Fleischer, Charles, Pergolizzi, Joseph, Zampogna, Gianpietro, Duval, Elizabeth, Hishmeh, Janan, LeQuang, Jo Ann, Taylor, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261842/
https://ncbi.nlm.nih.gov/pubmed/28176913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PPA.S78042
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