Peripherally acting μ-opioid receptor antagonists as treatment options for constipation in noncancer pain patients on chronic opioid therapy

Opioid-induced constipation (OIC), a prevalent and distressing side effect of opioid therapy, does not reliably respond to treatment with conventional laxatives. OIC can be a treatment-limiting adverse event. Recent advances in medications with peripherally acting μ-opioid receptor antagonists, such...

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Detalhes bibliográficos
Publicado no:Patient Prefer Adherence
Main Authors: Pergolizzi, Joseph V, Raffa, Robert B, Pappagallo, Marco, Fleischer, Charles, Pergolizzi, Joseph, Zampogna, Gianpietro, Duval, Elizabeth, Hishmeh, Janan, LeQuang, Jo Ann, Taylor, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261842/
https://ncbi.nlm.nih.gov/pubmed/28176913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PPA.S78042
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