The Use of Peripheral μ-Opioid Receptor Antagonists (PAMORA) in the Management of Opioid-Induced Constipation: An Update on Their Efficacy and Safety

Peripherally acting μ-opioid receptor antagonists (PAMORAs) constitute a class of drugs which reverse opioid-induced constipation (OIC) with similar opioid analgesic effects. OIC differs from other forms of constipation in that it is an iatrogenic condition that occurs when an opioid acts on the den...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Pergolizzi Jr, Joseph V, Christo, Paul J, LeQuang, Jo Ann, Magnusson, Peter
Format: Artigo
Language:Inglês
Published: Dove 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075239/
https://ncbi.nlm.nih.gov/pubmed/32210534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S221278
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