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Maximum Entropy Framework for Predictive Inference of Cell Population Heterogeneity and Responses in Signaling Networks

Predictive models of signaling networks are essential for understanding cell population heterogeneity and designing rational interventions in disease. However, using computational models to predict heterogeneity of signaling dynamics is often challenging because of the extensive variability of bioch...

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Bibliographic Details
Published in:Cell Syst
Main Authors: Dixit, Purushottam D., Lyashenko, Eugenia, Niepel, Mario, Vitkup, Dennis
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047530/
https://ncbi.nlm.nih.gov/pubmed/31864963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.11.010
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