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Maximum Entropy Framework for Predictive Inference of Cell Population Heterogeneity and Responses in Signaling Networks

Predictive models of signaling networks are essential for understanding cell population heterogeneity and designing rational interventions in disease. However, using computational models to predict heterogeneity of signaling dynamics is often challenging because of the extensive variability of bioch...

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Vydáno v:Cell Syst
Hlavní autoři: Dixit, Purushottam D., Lyashenko, Eugenia, Niepel, Mario, Vitkup, Dennis
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047530/
https://ncbi.nlm.nih.gov/pubmed/31864963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.11.010
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