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Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

Detecting relative rather than absolute changes in extracellular signals enables cells to make decisions in constantly fluctuating environments. It is currently not well understood how mammalian signaling networks store the memories of past stimuli and subsequently use them to compute relative signa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Lyashenko, Eugenia, Niepel, Mario, Dixit, Purushottam D, Lim, Sang Kyun, Sorger, Peter K, Vitkup, Dennis
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046471/
https://ncbi.nlm.nih.gov/pubmed/31961323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50342
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