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Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction
Large-scale protein signalling networks are useful for exploring complex biochemical pathways but do not reveal how pathways respond to specific stimuli. Such specificity is critical for understanding disease and designing drugs. Here we describe a computational approach—implemented in the free CNO...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824489/ https://ncbi.nlm.nih.gov/pubmed/19953085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.87 |
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