Detecting and Removing Inconsistencies between Experimental Data and Signaling Network Topologies Using Integer Linear Programming on Interaction Graphs

Cross-referencing experimental data with our current knowledge of signaling network topologies is one central goal of mathematical modeling of cellular signal transduction networks. We present a new methodology for data-driven interrogation and training of signaling networks. While most published me...

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Detaylı Bibliyografya
Asıl Yazarlar: Melas, Ioannis N., Samaga, Regina, Alexopoulos, Leonidas G., Klamt, Steffen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764019/
https://ncbi.nlm.nih.gov/pubmed/24039561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003204
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