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Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

Detecting relative rather than absolute changes in extracellular signals enables cells to make decisions in constantly fluctuating environments. It is currently not well understood how mammalian signaling networks store the memories of past stimuli and subsequently use them to compute relative signa...

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Опубликовано в: :eLife
Главные авторы: Lyashenko, Eugenia, Niepel, Mario, Dixit, Purushottam D, Lim, Sang Kyun, Sorger, Peter K, Vitkup, Dennis
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046471/
https://ncbi.nlm.nih.gov/pubmed/31961323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50342
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