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Maximum Entropy Framework for Predictive Inference of Cell Population Heterogeneity and Responses in Signaling Networks

Predictive models of signaling networks are essential for understanding cell population heterogeneity and designing rational interventions in disease. However, using computational models to predict heterogeneity of signaling dynamics is often challenging because of the extensive variability of bioch...

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發表在:Cell Syst
Main Authors: Dixit, Purushottam D., Lyashenko, Eugenia, Niepel, Mario, Vitkup, Dennis
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047530/
https://ncbi.nlm.nih.gov/pubmed/31864963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.11.010
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