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Quantifying Extrinsic Noise in Gene Expression Using the Maximum Entropy Framework
We present a maximum entropy framework to separate intrinsic and extrinsic contributions to noisy gene expression solely from the profile of expression. We express the experimentally accessible probability distribution of the copy number of the gene product (mRNA or protein) by accounting for possib...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4098093/ https://ncbi.nlm.nih.gov/pubmed/23790383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.010 |
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