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Quantifying Extrinsic Noise in Gene Expression Using the Maximum Entropy Framework

We present a maximum entropy framework to separate intrinsic and extrinsic contributions to noisy gene expression solely from the profile of expression. We express the experimentally accessible probability distribution of the copy number of the gene product (mRNA or protein) by accounting for possib...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Dixit, Purushottam D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098093/
https://ncbi.nlm.nih.gov/pubmed/23790383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.010
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