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The structure of a Mycobacterium tuberculosis heme-degrading protein, MhuD, variant in complex with its product

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, requires iron for survival. In Mtb, MhuD is the cytosolic protein that degrades imported heme. MhuD is distinct, both in sequence and structure, from canonical heme oxygenases (HOs) but homologous with IsdG-type proteins. Canonic...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Chao, Alex, Burley, Kalistyn H., Sieminski, Paul J., de Miranda, Rodger, Chen, Xiaorui, Mobley, David L., Goulding, Celia W.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045704/
https://ncbi.nlm.nih.gov/pubmed/31638374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00726
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