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A single mutation in the Mycobacterium tuberculosis heme-degrading protein, MhuD, results in different products
Mycobacterium tuberculosis heme-degrading protein MhuD degrades heme to mycobilin isomers and iron, while its closest homologs from Staphylococcus aureus, IsdG and IsdI, degrade heme to staphylobilin isomers, formaldehyde and iron. Superposition of the structures of the heme bound complexes reveal t...
Guardat en:
| Publicat a: | Biochemistry |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6568316/ https://ncbi.nlm.nih.gov/pubmed/30605595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01198 |
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