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The affinity of MhuD for heme is consistent with a heme degrading function in vivo
MhuD is a protein found in mycobacteria that can bind up to two heme molecules per protein monomer and catalyze the degradation of heme to mycobilin in vitro. Here the K(d1) for heme dissociation from heme-bound MhuD was determined to be 7.6 ± 0.8 nM and the K(d2) for heme dissocation from diheme-bo...
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| Udgivet i: | Metallomics |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6529808/ https://ncbi.nlm.nih.gov/pubmed/30239544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8mt00238j |
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