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The structure of a Mycobacterium tuberculosis heme-degrading protein, MhuD, variant in complex with its product
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, requires iron for survival. In Mtb, MhuD is the cytosolic protein that degrades imported heme. MhuD is distinct, both in sequence and structure, from canonical heme oxygenases (HOs) but homologous with IsdG-type proteins. Canonic...
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| Publicado en: | Biochemistry |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7045704/ https://ncbi.nlm.nih.gov/pubmed/31638374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00726 |
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