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Probing the Conformational and Energy Landscapes of KRAS Membrane Orientation

Membrane reorientation of oncogenic RAS proteins is emerging as an important modulator of their functions. Previous studies have shown that the most common orientations include those with either the three C-terminal α-helices (OS1) or N-terminal β-strands (OS2) of the catalytic domain facing the mem...

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Pubblicato in:J Phys Chem B
Autori principali: Prakash, Priyanka, Gorfe, Alemayehu A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045699/
https://ncbi.nlm.nih.gov/pubmed/31554397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b05796
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