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Probing the Conformational and Energy Landscapes of KRAS Membrane Orientation

Membrane reorientation of oncogenic RAS proteins is emerging as an important modulator of their functions. Previous studies have shown that the most common orientations include those with either the three C-terminal α-helices (OS1) or N-terminal β-strands (OS2) of the catalytic domain facing the mem...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Prakash, Priyanka, Gorfe, Alemayehu A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045699/
https://ncbi.nlm.nih.gov/pubmed/31554397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b05796
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