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Overview of simulation studies on the enzymatic activity and conformational dynamics of the GTPase Ras

Over the last 40 years, we have learnt a great deal about the Ras onco-proteins. These intracellular molecular switches are essential for the function of a variety of physiological processes, including signal transduction cascades responsible for cell growth and proliferation. Molecular simulations...

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Detalhes bibliográficos
Publicado no:Mol Simul
Main Authors: Prakash, Priyanka, Gorfe, Alemayehu A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610817/
https://ncbi.nlm.nih.gov/pubmed/26491216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08927022.2014.895000
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