Loading...

Ras Conformational Switching: Simulating Nucleotide-Dependent Conformational Transitions with Accelerated Molecular Dynamics

Ras mediates signaling pathways controlling cell proliferation and development by cycling between GTP- and GDP-bound active and inactive conformational states. Understanding the complete reaction path of this conformational change and its intermediary structures is critical to understanding Ras sign...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Grant, Barry J., Gorfe, Alemayehu A., McCammon, J. Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651530/
https://ncbi.nlm.nih.gov/pubmed/19300489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000325
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!