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Conformational Selection in G-Proteins: Lessons from Ras and Rho
The induced fit model has traditionally been invoked to describe the activating conformational change of the monomeric G-proteins, such as Ras and Rho. With this scheme, the presence or absence of the γ-phosphate of GTP leads to an instantaneous switch in conformation. Here we describe atomistic mol...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998626/ https://ncbi.nlm.nih.gov/pubmed/21112273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.020 |
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