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Large conformational changes in proteins: signaling and other functions
Guanine and adenine nucleotide triphosphatases, such as Ras proteins and protein kinases, undergo large conformational changes upon ligand binding in the course of their functions. New computer simulation methods have combined with experimental studies to deepen our understanding of these phenomena....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866511/ https://ncbi.nlm.nih.gov/pubmed/20060708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.12.004 |
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