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The Distinct Conformational Dynamics of K-Ras and H-Ras A59G
Ras proteins regulate signaling cascades crucial for cell proliferation and differentiation by switching between GTP- and GDP-bound conformations. Distinct Ras isoforms have unique physiological functions with individual isoforms associated with different cancers and developmental diseases. Given th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936511/ https://ncbi.nlm.nih.gov/pubmed/20838576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000922 |
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