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Mapping the nucleotide and isoform dependent structural and dynamical features of Ras proteins

Ras GTPases are conformational switches controlling cell proliferation, differentiation and development. Despite their prominent role in many forms of cancer, the mechanism of conformational transition between inactive GDP- and active GTP-bound states remains unclear. Here we describe a detailed ana...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gorfe, Alemayehu A., Grant, Barry J., McCammon, J. Andrew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519881/
https://ncbi.nlm.nih.gov/pubmed/18547521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.03.009
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