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Mapping the nucleotide and isoform dependent structural and dynamical features of Ras proteins

Ras GTPases are conformational switches controlling cell proliferation, differentiation and development. Despite their prominent role in many forms of cancer, the mechanism of conformational transition between inactive GDP- and active GTP-bound states remains unclear. Here we describe a detailed ana...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gorfe, Alemayehu A., Grant, Barry J., McCammon, J. Andrew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519881/
https://ncbi.nlm.nih.gov/pubmed/18547521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.03.009
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