Nalaganje...
The KRAS and other prenylated polybasic domain membrane anchors recognize phosphatidylserine acyl chain structure
KRAS interacts with the inner leaflet of the plasma membrane (PM) using a hybrid anchor that comprises a lysine-rich polybasic domain (PBD) and a C-terminal farnesyl chain. Electrostatic interactions have been envisaged as the primary determinant of interactions between KRAS and membranes. Here, we...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8017956/ https://ncbi.nlm.nih.gov/pubmed/33526670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014605118 |
| Oznake: |
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