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A novel prenyl-polybasic domain code determines lipid-binding specificity of the K-Ras membrane anchor
Ras proteins must localize to the plasma membrane (PM) for biological function. The membrane anchor of the K-Ras4B isoform comprises a farnesylated and methylated C-terminal cysteine together with an adjacent hexa-lysine polybasic domain (PBD). Traditionally, polybasic sequences have been thought to...
Sparad:
| I publikationen: | Small GTPases |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Taylor & Francis
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549719/ https://ncbi.nlm.nih.gov/pubmed/29239694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1379583 |
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