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RAS Nanoclusters Selectively Sort Distinct Lipid Headgroups and Acyl Chains
RAS proteins are lipid-anchored small GTPases that switch between the GTP-bound active and GDP-bound inactive states. RAS isoforms, including HRAS, NRAS and splice variants KRAS4A and KRAS4B, are some of the most frequently mutated proteins in cancer. In particular, constitutively active mutants of...
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| Publicado no: | Front Mol Biosci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8245699/ https://ncbi.nlm.nih.gov/pubmed/34222339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.686338 |
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