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Segregation of Negatively Charged Phospholipids by the Polycationic and Farnesylated Membrane Anchor of Kras

The Kras protein, a member of the Ras family of bio-switches that are frequently mutated in cancer and developmental disorders, becomes functional when anchored to the inner surface of the plasma membrane. It is well known that membrane attachment involves the farnesylated and poylcationic C-terminu...

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Bibliografske podrobnosti
Main Authors: Janosi, Lorant, Gorfe, Alemayehu A.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998625/
https://ncbi.nlm.nih.gov/pubmed/21112291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.031
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