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Probing the Conformational and Energy Landscapes of KRAS Membrane Orientation
Membrane reorientation of oncogenic RAS proteins is emerging as an important modulator of their functions. Previous studies have shown that the most common orientations include those with either the three C-terminal α-helices (OS1) or N-terminal β-strands (OS2) of the catalytic domain facing the mem...
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| Udgivet i: | J Phys Chem B |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7045699/ https://ncbi.nlm.nih.gov/pubmed/31554397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b05796 |
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