TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis

Myeloid-derived suppressor cells (MDSCs) are “polarized” myeloid cells that effectively promote tumorigenesis by inhibiting antitumor immunity. How myeloid cells acquire the protumoral properties during tumorigenesis is poorly understood. We report here that the polarity protein TIPE2 (tumor necrosi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Yan, Dehong, Wang, Jinghui, Sun, Honghong, Zamani, Ali, Zhang, Honglin, Chen, Weihong, Tang, Aifa, Ruan, Qingguo, Yang, Xiaolu, Chen, Youhai H., Wan, Xiaochun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041705/
https://ncbi.nlm.nih.gov/pubmed/31662347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182005
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