Directing leukocyte polarization and migration by the phosphoinositide transfer protein TIPE2

Leukocyte polarization toward chemoattractants is essential for directed leukocyte migration, or chemotaxis. How leukocytes acquire polarity upon encountering chemical gradients is not well understood. We report here that leukocyte polarity is generated by TIPE2 (TNFAIP8L2), a transfer protein of ph...

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Publicado en:Nat Immunol
Autores principales: Fayngerts, Svetlana A., Wang, Zhaojun, Zamani, Ali, Sun, Honghong, Boggs, Amanda E., Porturas, Thomas P., Xie, Weidong, Lin, Mei, Cathopoulis, Terry, Goldsmith, Jason R., Vourekas, Anastassios, Chen, Youhai H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690821/
https://ncbi.nlm.nih.gov/pubmed/29058702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3866
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