TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection

Phagocytosis and oxidative burst are two major effector arms of innate immunity. Although it is known that both are activated by Toll-like receptors (TLRs) and Rac GTPases, how their strengths are controlled in quiescent and TLR-activated cells is not clear. We report here that TIPE2 (TNFAIP8L2) ser...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Zhaojun, Fayngerts, Svetlana, Wang, Peng, Sun, Honghong, Johnson, Derek S., Ruan, Qingguo, Guo, Wei, Chen, Youhai H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458374/
https://ncbi.nlm.nih.gov/pubmed/22949657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204525109
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