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The Anti-inflammatory TIPE2 Is an Inhibitor of the Oncogenic Ras
The connection between cancer and inflammation is widely recognized; yet the underlying molecular mechanisms are poorly understood. We report here that TIPE2 provides a molecular bridge from inflammation to cancer by targeting the Ras signaling pathway. TIPE2 binds the Ras-interacting domain of the...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299909/ https://ncbi.nlm.nih.gov/pubmed/22326055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.006 |
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