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Small molecule inhibitors of RAS proteins with oncogenic mutations

RAS proteins control a number of essential cellular processes as molecular switches in the human body. Presumably due to their important signalling role, RAS proteins are among the most frequently mutated oncogenes in human cancers. Hence, numerous efforts were done to develop appropriate therapies...

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Orgován, Zoltán, Keserű, György M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680341/
https://ncbi.nlm.nih.gov/pubmed/32770300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09911-9
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