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Small molecule inhibitors of RAS proteins with oncogenic mutations

RAS proteins control a number of essential cellular processes as molecular switches in the human body. Presumably due to their important signalling role, RAS proteins are among the most frequently mutated oncogenes in human cancers. Hence, numerous efforts were done to develop appropriate therapies...

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Podrobná bibliografie
Vydáno v:Cancer Metastasis Rev
Hlavní autoři: Orgován, Zoltán, Keserű, György M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680341/
https://ncbi.nlm.nih.gov/pubmed/32770300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09911-9
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