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TIPE2 Controls Innate Immunity to RNA by Targeting the PI3K–Rac Pathway

RNA receptors such as TLR3 and RIG-I/MDA5 play essential roles in innate immunity to RNA viruses. However, how innate immunity to RNAs is controlled at the molecular level is not well understood. We describe here a new regulatory pathway of anti-RNA immunity that comprises PI3K (phosphoinositide kin...

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Bibliografski detalji
Glavni autori: Sun, Honghong, Zhuang, Guohong, Chai, Lihui, Wang, Zhaojun, Johnson, Derek, Ma, Yuanfang, Chen, Youhai H.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436961/
https://ncbi.nlm.nih.gov/pubmed/22904303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103477
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