TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis

Myeloid-derived suppressor cells (MDSCs) are “polarized” myeloid cells that effectively promote tumorigenesis by inhibiting antitumor immunity. How myeloid cells acquire the protumoral properties during tumorigenesis is poorly understood. We report here that the polarity protein TIPE2 (tumor necrosi...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Yan, Dehong, Wang, Jinghui, Sun, Honghong, Zamani, Ali, Zhang, Honglin, Chen, Weihong, Tang, Aifa, Ruan, Qingguo, Yang, Xiaolu, Chen, Youhai H., Wan, Xiaochun
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041705/
https://ncbi.nlm.nih.gov/pubmed/31662347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182005
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