Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires

Antibodies from B-cell clonal lineages share sequence and structural properties as well as epitope specificity. Clonally unrelated antibodies can similarly share sequence and specificity properties and are said to be convergent. Convergent antibody responses against several antigens have been descri...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Hsiao, Yi-Chun, Chen, Ying-Jiun J., Goldstein, Leonard D., Wu, Jia, Lin, Zhonghua, Schneider, Kellen, Chaudhuri, Subhra, Antony, Aju, Bajaj Pahuja, Kanika, Modrusan, Zora, Seshasayee, Dhaya, Seshagiri, Somasekar, Hötzel, Isidro
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039645/
https://ncbi.nlm.nih.gov/pubmed/32041466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1722541
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