Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires

Antibodies from B-cell clonal lineages share sequence and structural properties as well as epitope specificity. Clonally unrelated antibodies can similarly share sequence and specificity properties and are said to be convergent. Convergent antibody responses against several antigens have been descri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:MAbs
Prif Awduron: Hsiao, Yi-Chun, Chen, Ying-Jiun J., Goldstein, Leonard D., Wu, Jia, Lin, Zhonghua, Schneider, Kellen, Chaudhuri, Subhra, Antony, Aju, Bajaj Pahuja, Kanika, Modrusan, Zora, Seshasayee, Dhaya, Seshagiri, Somasekar, Hötzel, Isidro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2020
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039645/
https://ncbi.nlm.nih.gov/pubmed/32041466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1722541
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