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Analysis of the effect of promoter type and skin pretreatment on antigen expression and antibody response after gene gun-based immunization

Monoclonal antibodies (mAbs) have enabled numerous basic research discoveries and therapeutic approaches for many protein classes. However, there still exist a number of target classes, such as multi-pass membrane proteins, for which antibody discovery is difficult, due in part to lack of high quali...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Vij, Rajesh, Lin, Zhonghua, Schneider, Kellen, Seshasayee, Dhaya, Koerber, James T.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983433/
https://ncbi.nlm.nih.gov/pubmed/29856790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197962
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